Research

MION2
Orbitrap

The High-Resolution
Chemical Ionization Mass Spectrometer
Wherever science takes you.
MION2 Orbitrap Exploris™ delivers revolutionary performance in the lab or the field.

‣ Superior Resolving Power    
120,000 - 240,000 for clear molecular separation

‣ Fast Polarity and Reagent Switching
Switch in seconds without compromising results

‣ Sub-ppt Detection Limits
Confidently detect trace-level compounds

‣ Maintenance-Free Solid Reagents
Fewer interventions. Consistent uptime.

‣ Wide chemical coverage
VOCs · Amines · Acids · HOMs


‍Ready to push the boundaries of analytical power?
Get in touch

Ionization

We pioneered fast polarity and reagent switching, extending it to multi-pressure ionization and introduced an entirely new class of reagents.

This provides highly selective, dual-pressure ion–molecule chemistry across a wide range of compounds—from trace gases to multifunctional organics—all captured in real time under ambient conditions.
MION2

Sampling

Our modular sampling platform enables flexible, unified workflows for gas-phase analysis, filter desorption, and online particle desorption—all within a single framework.

This adaptability supports both real-time and integrated sampling across laboratory and field deployments, extending chemical access from volatile gases to semi-volatile and particulate species.

Molecular Clarity

As shown here, compounds of distinct chemical relevance remain indistinguishable at conventional resolutions. It is only beyond R=100,000 that their unique identities become accessible.

‍For complex atmospheric mixtures, high-resolution mass spectrometry is no longer an enhancement; it is the prerequisite for molecular-level attribution.

Download white paper here.

Solid Performance

A single Multi-Pressure CIMS system operating with solid reagents reveals a wide array of α-pinene oxidation products—across volatilities and functionalities—with remarkable sensitivity and stability.

‍By merging solid reagent delivery with multi-pressure ionization, we achieve comprehensive, field-ready performance in a single configuration.

Download webinar slides here.

Resources

White paper: The Next Decade of Atmospheric Science Will Be Driven by High-er Resolution

This white paper explains how insufficient resolution leads to ambiguity—and how new high-resolution mass spectrometry is essential for identifying what truly matters in air chemistry.
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Mobile Orbitrap Mass Spectrometry: Stability and Performance in Motion

Historically, Orbitrap mass spectrometers have been considered large, power-intensive, and lab-bound instruments -- but times have changed!
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Analytical Chemistry: Introducing Multi-Pressure Chemical Ionization Mass Spectrometry

MPCIMS enables simultaneous detection of Volatile Organic Compounds and their oxidized reaction products within a single gas stream.
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Analytical Chemistry: Fast Polarity Switching of Chemical Ionization Orbitrap MS

The polarity switching MION-Orbitrap system is shown to be a versatile and powerful technique for the online analysis of a wide range of reactive trace species.
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News

Upcoming Webinar: Harnessing MPCI with Solid-State Reagents

13.6.2025
Research
We’re excited to invite you to a 45-minute live webinar on July 2, 2025, where our lead developers will showcase the latest advances in Multi-Pressure Chemical Ionization (MPCI) using all-solid-state reagent for nitrate (NO₃⁻), uronium (from urea), and fluoranthene.
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Karsa Presenting at ASMS 2025 in Baltimore

28.5.2025
Research
Karsa will be attending the ASMS Conference on Mass Spectrometry and Allied Topics in Baltimore, June 1–5, 2025. Our team will present new developments in chemical ionization mass spectrometry, including novel reagents, instrumentation, and application workflows.
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Karsa at EGU 2025 – Join Us in Vienna!

25.4.2025
Research
Karsa is heading to the EGU General Assembly 2025 in Vienna, where we’ll be sharing our latest research and connecting with the atmospheric science community. Join us at our MION user get-together on Thursday evening, featuring a live demo of the MION2-Orbitrap system at TU Vienna and a casual dinner to follow.
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